Partial epigenetic reprogramming

Topic

Partial epigenetic reprogramming is an emerging biotechnology and cellular rejuvenation technique that involves the transient expression of reprogramming factors (such as the Yamanaka factors) to reverse age-associated epigenetic changes. Unlike full reprogramming, which reverts somatic cells back to pluripotent stem cells, partial reprogramming resets the cellular aging clock and restores youthful function while preserving the cell's original identity. This approach is actively being researched as a therapeutic strategy to treat age-related diseases and extend healthspan.