AO252
Product
by Coiled Therapeutics
An investigational therapeutic program licensed for worldwide development by Coiled Therapeutics; the excerpt presents it as a central drug-development asset.
What experts have said about AO252
10 statements · 9 positive · 1 mixed
AO-252 reaches brain tissue at roughly blood-equivalent levels.
“Our ability to actually have pretty much on a 1-to-1 level of what the, the in the blood versus what's in the brain”
Open the episode · S11 Ep68: Sunday Roast featuring Coiled Therapeutics PLC and Halo Resources #COIL #HALO #EPP #DELTA #KEN #AEGListen at 11:03
AO-252 has an approximately 80% clinical benefit rate.
“our clinical benefit rate is at about 80%.”
Open the episode · S11 Ep68: Sunday Roast featuring Coiled Therapeutics PLC and Halo Resources #COIL #HALO #EPP #DELTA #KEN #AEGListen at 13:08
AO-252 reduced a tumor by 30% in a heavily pretreated patient.
“it still takes 30% of the tumor down.”
Open the episode · S11 Ep68: Sunday Roast featuring Coiled Therapeutics PLC and Halo Resources #COIL #HALO #EPP #DELTA #KEN #AEGListen at 13:41
AO-252 can convert immunologically cold tumors into hot tumors.
“We're able to transform that and really make it into a hot tumor.”
Open the episode · S11 Ep68: Sunday Roast featuring Coiled Therapeutics PLC and Halo Resources #COIL #HALO #EPP #DELTA #KEN #AEGListen at 17:11
AO-252 could address a market approaching or exceeding $100 billion.
“you could be reaching anywhere close to $100 billion plus.”
Open the episode · S11 Ep68: Sunday Roast featuring Coiled Therapeutics PLC and Halo Resources #COIL #HALO #EPP #DELTA #KEN #AEGListen at 25:03
AO-252 may have applications beyond cancer.
“Could there potentially be other uses? Yes, potentially they can”
Open the episode · S11 Ep68: Sunday Roast featuring Coiled Therapeutics PLC and Halo Resources #COIL #HALO #EPP #DELTA #KEN #AEGListen at 29:23
AO-252 will become a major blockbuster and justify buying Coiled shares.
“this is going to be a huge blockbuster, we believe, and one that will definitely be worth the buying of the share.”
Open the episode · S11 Ep68: Sunday Roast featuring Coiled Therapeutics PLC and Halo Resources #COIL #HALO #EPP #DELTA #KEN #AEGListen at 31:37
AO-252 is worth substantially more than its implied £6–8 million value.
“the value is much greater than that.”
Open the episode · S11 Ep68: Sunday Roast featuring Coiled Therapeutics PLC and Halo Resources #COIL #HALO #EPP #DELTA #KEN #AEGListen at 32:23
AO-252 has already demonstrated tumor effects below its maximum tolerated dose.
“we've already shown that that's the case, and we showed it with doses that aren't even at the maximum tolerated dose yet.”
Open the episode · S11 Ep68: Sunday Roast featuring Coiled Therapeutics PLC and Halo Resources #COIL #HALO #EPP #DELTA #KEN #AEGListen at 32:51
Coiled expects clinical answers on AO-252 within months, not years.
“we'll have our answers fairly quickly.”
Open the episode · S11 Ep68: Sunday Roast featuring Coiled Therapeutics PLC and Halo Resources #COIL #HALO #EPP #DELTA #KEN #AEGListen at 35:07
Statements are attributed to the speaker as said on the episode and reflect their view at the time, not PodLume's. They are not advice.
