Target Profiling

Topic

Target profiling is an essential pharmacological and biochemical process used in drug discovery to identify and map the comprehensive interaction network between small molecules (such as candidate drugs) and their cellular protein targets. By utilizing advanced techniques like chemical proteomics, activity-based protein profiling (ABPP), and in silico machine learning models, researchers can determine both intended therapeutic targets and unintended off-targets. This systematic characterization is crucial for understanding a drug's mechanism of action, predicting potential side effects, and assessing overall safety profiles early in the development pipeline.