NRF2 (Nuclear factor erythroid 2-related factor 2)

Topic

Nuclear factor erythroid 2-related factor 2 (NRF2) is a transcription factor that regulates the expression of antioxidant proteins, protecting cells against oxidative damage from injury and inflammation. It is a basic leucine zipper (bZIP) protein that binds to antioxidant response elements (AREs) in the promoter regions of various genes.