Insulin coma therapy

Work

by Manfred Sakel · 1927

Insulin coma therapy, also called insulin shock therapy, was a psychiatric treatment introduced in 1927 by Austrian-American psychiatrist Manfred Sakel. It involved repeatedly administering large doses of insulin to induce daily comas over several weeks, and was used mainly for schizophrenia before falling out of favor in the 1960s with the rise of neuroleptic drugs.