
DNA damage
Topic
DNA damage is an alteration in the chemical structure of DNA, such as a strand break, a missing nucleobase, or a chemically modified base. It occurs naturally through cellular metabolism or via environmental factors like radiation and toxins, and is distinct from a mutation, which is a change in the base sequence itself. Unrepaired DNA damage can lead to genomic instability, cellular senescence, or apoptosis, and is a major driver of aging and cancer.
2 episodes featuring DNA damage

The Diary Of A CEO with Steven Bartlett
Leading researcher argues cancer is a metabolic disease of the mitochondria
Reframing cancer as a metabolic disease opens up accessible, lifestyle-based prevention strategies and helper therapies that target how tumor cells generate energy.
Jul 16, 2026 · 1h 47m

The Joe Rogan Experience: Protect Our Parks
Science writer Rowan Jacobsen challenges modern medical advice on sun exposure
This episode challenges decades of dermatological advice, urging a shift from total sun avoidance to a nuanced understanding of human evolutionary biology.
Jun 18, 2026 · 2h 13m
