Andrew T. Scull

Andrew T. Scull

Person

Andrew T. Scull is a British-born sociologist and historian of psychiatry who is distinguished professor emeritus of sociology and science studies at the University of California, San Diego. He is known for his research on the social history of medicine and psychiatry and for books including *Madness in Civilization*, *Madhouse*, and *Desperate Remedies*.

Works by Andrew T. Scull

What Andrew T. Scull has said on podcasts

49 statements

  1. on Modern psychiatric treatmentsNegativeSep 17, 2026· Lex Fridman Podcast

    Psychiatry currently offers symptomatic treatments rather than cures.

    What we have available to us are symptomatic treatments, not cures.

    Listen at 10:57

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  2. on Trauma-focused PTSD treatmentNegativeSep 17, 2026· Lex Fridman Podcast

    Trauma confrontation during PTSD treatment can worsen symptoms for many patients.

    for many patients, it actually makes things worse.

    Listen at 12:07

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  3. on Antipsychotics and antidepressantsNegativeSep 17, 2026· Lex Fridman Podcast

    Antipsychotics and antidepressants are partially effective and fail for many patients.

    they're at best partially effective and they don't work for a significant fraction of patients who are given them.

    Listen at 12:27

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  4. on DSM-IIINegativeSep 17, 2026· Lex Fridman Podcast

    DSM-III was created because psychiatrists showed poor diagnostic agreement.

    that diagnostic system came into being because psychiatrists had a very hard time agreeing with one another about what was wrong with somebody.

    Listen at 14:00

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  5. on DSM diagnostic categoriesNegativeSep 17, 2026· Lex Fridman Podcast

    Reliable DSM diagnoses may not validly represent underlying psychiatric reality.

    that conclusion may or may not reflect the underlying reality of things

    Listen at 17:25

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  6. on NIMH psychiatric research fundingNegativeSep 17, 2026· Lex Fridman Podcast

    NIMH-funded neuroscience and genetics research produced no improvement for mentally ill people.

    after spending $20 billion, the lot of the mentally ill has improved not one bit

    Listen at 20:04

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  7. on NIMHNeutralSep 17, 2026· Lex Fridman Podcast

    NIMH increasingly treated mental illness as purely brain disease.

    NIMH increasingly focused on the idea that mental illness was purely a brain disease.

    Listen at 20:55

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  8. on Social factors in mental illnessNeutralSep 17, 2026· Lex Fridman Podcast

    Social factors play an important role in developing mental illness.

    there's abundant evidence from epidemiology that social factors play an important role, in the development of mental illness.

    Listen at 23:13

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  9. on DSM psychiatric categoriesNegativeSep 17, 2026· Lex Fridman Podcast

    Traditional psychiatric categories are increasingly viewed as unstable or potentially misleading.

    the categories that we have all become familiar with, that we've been told are real diseases like bipolar disorder, schizophrenia, major depression, are beginning to falter.

    Listen at 26:47

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  10. on Community mental-health careNegativeSep 17, 2026· Lex Fridman Podcast

    Community care failed to provide adequate substitutes for psychiatric asylums.

    community care is a shell game without a pea.

    Listen at 37:10

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  11. on Early psychiatric asylumsPositiveSep 17, 2026· Lex Fridman Podcast

    Early asylums helped some patients and enabled some recoveries.

    I do believe the early asylums actually did good work and that some patients did very well and recovered as a result of their stays.

    Listen at 45:18

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  12. on LobotomyNegativeSep 17, 2026· Lex Fridman Podcast

    The scientific basis of lobotomy was weak.

    the science behind it was shaky

    Listen at 57:46

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  13. on Malaria therapy for general paralysis of the insaneNegativeSep 17, 2026· Lex Fridman Podcast

    Claims about malarial treatment curing syphilitic insanity were greatly exaggerated.

    those claims were wildly exaggerated, but they were widely accepted.

    Listen at 1:08:57

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  14. on Insulin coma therapyNegativeSep 17, 2026· Lex Fridman Podcast

    Insulin coma therapy failed controlled clinical testing.

    when they were subjected to a controlled trial, they failed it.

    Listen at 1:25:39

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  15. on Electroconvulsive therapyPositiveSep 17, 2026· Lex Fridman Podcast

    ECT appears effective for severe, especially suicidal, depression.

    it seems to work in cases of depression, suicidal depression particularly.

    Listen at 1:32:05

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  16. on Modified ECTPositiveSep 17, 2026· Lex Fridman Podcast

    Muscle relaxants largely eliminated fractures associated with ECT.

    you did eliminate the fractures.

    Listen at 1:34:47

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  17. on Electroconvulsive therapyMixedSep 17, 2026· Lex Fridman Podcast

    ECT temporarily alleviates psychiatric symptoms rather than curing them.

    it temporarily alleviates the symptoms

    Listen at 1:35:20

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  18. on Schizophrenia geneticsNeutralSep 17, 2026· Lex Fridman Podcast

    Three hundred genetic variants explain about ten percent of schizophrenia susceptibility.

    if we use 300 small variations in the genome, we can account for about 10% of schizophrenia.

    Listen at 1:42:34

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  19. on Schizophrenia and bipolar disorderNegativeSep 17, 2026· Lex Fridman Podcast

    Some psychiatrists predict schizophrenia and bipolar disorder may be abandoned as distinct entities.

    there's no such thing as schizophrenia, there's no such thing as bipolar disorder

    Listen at 1:43:40

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  20. on Ketamine and psychedelics for depressionNegativeSep 17, 2026· Lex Fridman Podcast

    Ketamine and psychedelics are being promoted as miracle cures for depression.

    I see ketamine and psychedelics being propounded as a miracle cure for depression

    Listen at 1:45:17

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  21. on Ketamine and psychedelics for depressionNegativeSep 17, 2026· Lex Fridman Podcast

    Evidence supporting ketamine and psychedelics as depression cures is very weak.

    the evidence for that is enormously weak

    Listen at 1:45:25

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  22. on Negative scientific findingsPositiveSep 17, 2026· Lex Fridman Podcast

    Negative findings are important for scientific progress.

    negative findings are very important in science.

    Listen at 1:47:40

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  23. on ECT in mental hospitalsNegativeSep 17, 2026· Lex Fridman Podcast

    ECT was used as a disciplinary tool in many mid-century mental hospitals.

    ECT was used in the '50s and '60s as a tool of discipline in the hospitals.

    Listen at 1:57:10

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  24. on Electroconvulsive therapyPositiveSep 17, 2026· Lex Fridman Podcast

    Recent controlled trials provide enough evidence that ECT benefits some patients.

    there's enough evidence now that it's hard to say this never works.

    Listen at 2:01:03

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  25. on Combat-related psychological breakdownNegativeSep 17, 2026· Lex Fridman Podcast

    Up to one-quarter of soldiers experienced psychological breakdown in combat conditions.

    In combat conditions, as much as 25% of the soldiers broke down.

    Listen at 2:44:50

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  26. CBT-style therapies can be standardized, reproduced, and empirically tested.

    these therapies could be packaged. They could be reproduced. They could be tested to see whether they worked.

    Listen at 2:50:37

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  27. on CBT for mild depressionPositiveSep 17, 2026· Lex Fridman Podcast

    CBT may outperform antidepressants for milder depression with fewer side effects.

    for the milder forms depression, I think CBT works better than the drugs without some of the side effects that the drugs have.

    Listen at 2:54:58

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  28. CBT substantially improves outcomes for some patients.

    for some patients, this really does seem to improve things quite a lot.

    Listen at 2:56:22

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  29. on PsychopharmacologyNeutralSep 17, 2026· Lex Fridman Podcast

    Psychopharmacology emerged accidentally rather than from planned psychiatric drug development.

    the idea that a drug might be used to actually attack the underlying problem, it emerged by accident

    Listen at 2:58:16

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  30. on Antipsychotic drugsPositiveSep 17, 2026· Lex Fridman Podcast

    Antipsychotics reduce agitation, delusions, and hallucinations for many patients.

    they reduce the agitation, they reduce the delusions and the hallucinations

    Listen at 3:07:45

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  31. on Antipsychotic drugsNegativeSep 17, 2026· Lex Fridman Podcast

    Antipsychotics have limited effect on schizophrenia’s negative symptoms.

    the negative side of things, not so much or not at all.

    Listen at 3:09:19

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  32. on Antipsychotic drugsNegativeSep 17, 2026· Lex Fridman Podcast

    A significant share of psychotic patients do not respond to antipsychotic drugs.

    a significant number of psychotic patients are non-drug responders

    Listen at 3:09:33

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  33. on Psychiatric drug trialsNegativeSep 17, 2026· Lex Fridman Podcast

    Drug companies controlled much psychiatric trial data and selectively released results.

    the studies were funded by the drug companies who owned the data and controlled the data and only released what they chose to release

    Listen at 3:15:04

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  34. on FDA psychiatric drug approvalNegativeSep 17, 2026· Lex Fridman Podcast

    FDA approval could follow two successful trials despite many failed trials.

    if you had 2 that worked, that was enough.

    Listen at 3:15:31

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  35. on CATIE antipsychotic trialNegativeSep 17, 2026· Lex Fridman Podcast

    Sixty-seven to eighty-two percent of CATIE participants discontinued treatment.

    Between 67 and 82% of the patients, depending on which drug they were on, dropped out of the trial

    Listen at 3:16:42

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  36. on Second-generation antipsychoticsNegativeSep 17, 2026· Lex Fridman Podcast

    Second-generation antipsychotics commonly cause substantial weight gain and metabolic risks.

    If you take these pills, you will gain, in most cases, a of weight. 10, 20, 30, 40 pounds, 50 pounds.

    Listen at 3:17:14

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  37. on Personalized psychiatric prescribingNegativeSep 17, 2026· Lex Fridman Podcast

    Clinicians lack biological markers predicting individual psychiatric drug response.

    we have no biological markers at the moment that would tell us.

    Listen at 3:18:45

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  38. on Depression diagnosisNeutralSep 17, 2026· Lex Fridman Podcast

    Depression is now an extremely common psychiatric diagnosis.

    depression is the common cold of psychiatry.

    Listen at 3:21:49

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  39. on Autism diagnosisNeutralSep 17, 2026· Lex Fridman Podcast

    Autism diagnosis growth is driven more by loosened criteria than increased underlying prevalence.

    the huge increase in the number of diagnoses of autism is more driven by the fact he loosened the criteria for the diagnosis than it is because there are more actual cases.

    Listen at 3:24:04

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  40. on AntidepressantsMixedSep 17, 2026· Lex Fridman Podcast

    Antidepressants consistently beat placebo statistically but not always clinically.

    Every time you do a controlled study of these antidepressants, they beat placebo in a statistically significant margin, but not necessarily in a clinically significant margin.

    Listen at 3:29:11

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  41. on AntidepressantsNegativeSep 17, 2026· Lex Fridman Podcast

    Antidepressants provide only marginal benefit over placebo for most patients.

    for most patients, antidepressants are marginally better than placebo

    Listen at 3:30:08

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  42. on AntidepressantsNegativeSep 17, 2026· Lex Fridman Podcast

    Many antidepressant users experience complete loss of libido.

    lots of patients find a complete loss of libido

    Listen at 3:30:44

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  43. on NICE depression guidancePositiveSep 17, 2026· Lex Fridman Podcast

    NICE recommends CBT before antidepressant medication in relevant cases.

    NICE in England are saying use CBT as the first line, not drugs.

    Listen at 3:31:34

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  44. on Antidepressants for depressionNegativeSep 17, 2026· Lex Fridman Podcast

    At least forty percent of depressed patients may not respond to antidepressants.

    we're talking 40 or north of 40% who aren't responding.

    Listen at 3:32:12

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  45. on Medication for severe mental illnessPositiveSep 17, 2026· Lex Fridman Podcast

    People with severe psychiatric suffering should probably try medication.

    you probably need to try the drugs because the suffering is very intense

    Listen at 3:33:34

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  46. on Psychiatric research prioritiesPositiveSep 17, 2026· Lex Fridman Podcast

    Psychiatric research should expand beyond drugs, neuroscience, and genetics.

    psychiatric research needs to broaden.

    Listen at 3:33:49

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  47. on Social support and mental healthPositiveSep 17, 2026· Lex Fridman Podcast

    Social support and interaction substantially benefit mental health.

    helping people as much as we can with social supports and social interaction is tremendously important to people's mental health.

    Listen at 3:36:57

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  48. on Major mental illnessesNeutralSep 17, 2026· Lex Fridman Podcast

    Major mental illnesses likely have biological components.

    I would be astonished if the major forms of mental illness didn't have a biological component to them.

    Listen at 3:37:31

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung
  49. on Psychiatric medicationMixedSep 17, 2026· Lex Fridman Podcast

    Medication can help but cannot solve the full problem of mental illness.

    a less reliance on something as simple as giving people pills because that can help, but it's clearly not going to be the solution to the whole thing.

    Listen at 3:40:46

    Open the episode · #502 – Psychiatry, Insane Asylums, Mental Illness, ECT, Lobotomies, Freud & Jung

Statements are attributed to the speaker as said on the episode and reflect their view at the time, not PodLume's. They are not advice.

1 episode featuring Andrew T. Scull

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