Sep 22, 2026 · 7 min
Shopify, Moderna and On ride distinct catalysts
Shopify Gains, Moderna Climbs, On Rallies
The episode shows how AI partnerships, cancer-vaccine data and expansion plans can move very different companies’ shares.
- 1Shopify becomes the Nasdaq 100’s biggest gainer after announcing a deep partnership with Meta’s Muse AI agent.
- 2Moderna rises ahead of personalized cancer-vaccine data tied to Merck and messenger RNA technology.
- 3On Holding targets high-teens sales growth through golf, soccer and athlete partnerships while authorizing a $1 billion buyback.
Don't miss
On Holding pairs ambitious expansion into golf and soccer with authorization for up to $1 billion in share buybacks through 2029.
The brief
Shopify becomes the Nasdaq 100’s biggest gainer after its CEO announces a deep partnership with Meta’s Muse AI agent, raising questions about AI’s reach across other stocks.
The discussion turns to Moderna, whose shares climb ahead of personalized cancer-vaccine data connected to Merck and messenger RNA, against the backdrop of its sharply higher 2026 valuation.
On Holding’s move reflects an expansion story: the sportswear company expects high-teens sales growth while entering golf and soccer and building athlete partnerships.
The clearest tension arrives with On’s $1 billion buyback authorization through 2029: management is investing for growth while supporting a stock that has declined for the year.
Together, the movers show three market catalysts operating on different clocks—an AI partnership now, clinical data ahead and a multiyear consumer expansion plan.
What was said on this episode
8 statements · 6 positive · 1 negative · 1 neutral
The Meta partnership should enable agentic checkout through Shop Pay and Shopify stores.
“this partnership should essentially enable a Genic checkout with Shop Pay as well as across Shopify stores”
Listen at 1:12
Moderna shares rose following its planned cancer-vaccine data presentation.
“The stock is up. This is after reporting just yesterday that it'll present data on its personalized cancer vaccine.”
Listen at 1:55
Moderna shares have risen 520% so far in 2026.
“up 520% so far in 2026”
Listen at 2:16
Personalized cancer vaccines could be highly significant.
“this idea of these personalized cancer vaccines and how significant this could be”
Listen at 2:35
On Holding expects high-teens sales growth over the next few years.
“the company said it expects sales growth in the high teens over the next few years”
Listen at 3:47
On Holding expects net sales of at least 5.6 billion Swiss francs by 2029.
“it expects net sales to grow by at least 5.6 billion Swiss francs, as I mentioned, by 2029”
Listen at 4:09
On Holding is trying to compete with Nike and Adidas.
“trying to compete against the likes of Nike and Adidas”
Listen at 4:44
On Holding shares are down about 36% in 2026.
“the stock is still having a bit of a rough year, down about 36% so far for 2026”
Listen at 4:49
Statements are attributed to the speaker as said on the episode and reflect their view at the time, not PodLume's. They are not advice.
Featuring
Mentioned
Shopify Inc.
Muse GlimmerListen to the full episode and explore every guest, topic, and moment on PodLume.