Aug 18, 2026 · 7 min
Amylyx surges on trial success while Klarna plunges on weak guidance
Closing Bell: Amylyx Pharmaceuticals Climbs, Targa Rises, Klarna Plunges
This episode details how clinical breakthroughs and executive shakeups are driving stark divergence between winning biotech firms and struggling fintech giants.
- 1Amylyx Pharmaceuticals shares surged following highly positive clinical trial results for its experimental drug therapy.
- 2Klarna faced a steep market decline after announcing lowered revenue expectations and key executive departures.
- 3A broader technology and semiconductor sell-off dragged down major industrial stocks like Caterpillar.
Don't miss
Amylyx Pharmaceuticals experiences a massive intraday surge following positive clinical trial results for its experimental drug.
The brief
A volatile trading session sees major shifts as clinical trial breakthrough news sends one biotech firm soaring, while executive departures and lowered revenue expectations trigger a sharp sell-off in the financial technology sector.
Amylyx Pharmaceuticals leads the market gainers with a massive intraday surge following positive clinical trial results for its experimental drug, while language learning platform Duolingo rallies on the heels of an analyst upgrade.
Swedish fintech firm Klarna plunges into a steep decline as investors react to disappointing revenue guidance and key executive departures, highlighting growing pains and shifting sentiment in the digital lending space.
The broader market faces headwinds from a widespread sell-off in technology and semiconductor stocks, dragging down heavy machinery giant Caterpillar alongside updates on rising bond yields.
What was said on this episode
7 statements · 5 positive · 2 negative
Targa was the S&P 500’s top gainer, rising more than 7%.
“Targa is the number one gainer gainer, excuse me, in the S&P 500 that stock is up more than 7%”
Listen at 1:46
Targa’s shares rose after signing a 20-year midstream agreement with ExxonMobil subsidiaries.
“Targa up after the energy company signed a new 20 year fee based integrated midstream agreement with ExxonMobil subsidiaries”
Listen at 1:55
Davidson upgraded Duolingo to buy, citing accelerating daily active-user metrics.
“Davidson upgrading the language learning platform to buy from neutral, citing a turning point in acceleration of daily active user metrics”
Listen at 2:39
Davidson’s Duolingo price target implied more than 20% upside.
“So price Target set at 160 a share. Stock closed just below $140 a share. So you're looking at more than 20% upside.”
Listen at 2:47
Klarna cut annual revenue expectations amid FX pressures and weaker German consumer spending.
“Klarna, the payments firm fell by more than 20% after cutting its revenue expectations for the year amid foreign exchange pressures and weaker consumer spending in Germany”
Listen at 3:03
Data-center construction has boosted Caterpillar shares through power-equipment purchases.
“investors have boosted the stock as companies go after building more data centers. And they purchased Caterpillar power generation equipment.”
Listen at 4:36
The 30-year Treasury yield remained near its highest level since 2007.
“the 30 year yield, 5.2.8% still sitting near the high since 2007”
Listen at 5:03
Statements are attributed to the speaker as said on the episode and reflect their view at the time, not PodLume's. They are not advice.
Featuring
Klarna
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